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Acupuncture  (from  Lat.  acus,  "needle",  and  pungere, "prick") or in Standard Mandarin,  zhen  bian (a related word zhen jiu refers to acupuncture  together  with  moxibustion)  is  a  technique  of  inserting  and  manipulating filiform  needles  into points on the body with the aim of relieving pain and for therapeutic purposes. Acupuncture is  thought  to  have  originated  in  China  and  is  most  commonly associated with Traditional Chinese Medicine (TCM). Different types of acupuncture (Classical Chinese,  Japanese,  Tibetan,  and  Korean  acupuncture)  are practiced and taught throughout the world.

The  effectiveness  of  acupuncture  remains  controversial  in  the scientific community, according to a review by Edzard  Ernst  and  colleagues  in 2 007,  which  found  that  the  body  of  evidence  was  growing,  research  is  active, and  that  the "emerging clinical evidence seems to imply that acupuncture is effective for some but not all conditions". Researchers  using  the  protocols  of   evidence-based  medicine  have  found  good  evidence  that acupuncture is moderately effective in preventing nausea. There is conflicting evidence  that  it  can  treat  chronic low back pain, and moderate  evidence of  efficacy  for  neck  pain  and  headache. For  most  other  conditions reviewers  have  found  either  a  lack  of  efficacy  (e.g., help in quitting smoking  or have concluded that there is insufficient evidence to determine whether acupuncture  is  effective (e.g.,  treating  shoulder  pain. While  little  is known  about  the  mechanisms  by which acupuncture may act, a review of neuroimaging research suggests that specific  acupuncture  points  have  distinct  effects  on  cerebral  activity  in  specific areas that are not otherwise predictable anatomically.

The  WHO, the  Nationa l Center   for   Complementary  and  Alternative  Medicine  (NCCAM),  the  National Institutes of Health (NIH), the American Medical Association (AMA) and various government reports have also studied and commented on the efficacy of acupuncture. There is also general agreement that acupuncture is  safe when administered by well-trained practitioners, and that further research is warranted.

Traditional  Chinese  medicine's  acupuncture  theory  predates  the use of the modern scientific method, and has received various criticisms based on modern  scientific thinking. There  is  no  generally-accepted  anatomical  or histological  basis  for  the  existence  of  acupuncture points or meridians. Acupuncturists tend to perceive TCM concepts  in  functional  rather  than  structural  terms,  i.e.  as  being  usefu l in  guiding  evaluation  and  care   of patients.Scientists have reported a cultural bias in scientific studies of acupuncture.